Insuliini ja keramidi- mitä koorelaatiota

Improved insulin sensitivity after exercise training is linked to reduced plasma C14:0 ceramide in obesity and type 2 diabetes.

Kasumov T, Solomon TP, Hwang C, Huang H, Haus JM, Zhang R, Kirwan JP.

Obesity (Silver Spring). 2015 May 12. doi: 10.1002/oby.21117. [Epub ahead of print]

PMID:

25966363

Select item 259595292.

Effect of pioglitazone on plasma ceramides in adults with metabolic syndrome.

Warshauer JT, Lopez X, Gordillo R, Hicks J, Holland WL, Anuwe E, Blankfard MB, Scherer PE, Lingvay I.

Diabetes Metab Res Rev. 2015 May 10. doi: 10.1002/dmrr.2662. [Epub ahead of print]

PMID:

25959529

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Select item 259541973.

Sphingosine 1-phosphate signaling pathway in inner ear biology. New therapeutic strategies for hearing loss?

Romero-Guevara R, Cencetti F, Donati C, Bruni P.

Front Aging Neurosci. 2015 Apr 23;7:60. doi: 10.3389/fnagi.2015.00060. eCollection 2015. Review.

PMID:

25954197

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Select item 259158514.

Metabolomic profiling in liver of adiponectin knockout mice uncovers lysophospholipid metabolism as an important target of adiponectin action.

Liu Y, Sen S, Wannaiampikul S, Palanivel R, Hoo RL, Isserlin R, Bader GD, Tungtrongchitr R, Deshaies Y, Xu A, Sweeney G.

Biochem J. 2015 Apr 27. [Epub ahead of print]

PMID:

25915851

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Select item 258792845.

Drivers of age-related inflammation and strategies for healthspan extension.

Goldberg EL, Dixit VD.

Immunol Rev. 2015 May;265(1):63-74. doi: 10.1111/imr.12295.

PMID:

25879284

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Select item 258302286.

Positive effects of voluntary running on metabolic syndrome-related disorders in non-obese hereditary hypertriacylglycerolemic rats.

Škop V, Malínská H, Trnovská J, Hüttl M, Cahová M, Blachnio-Zabielska A, Baranowski M, Burian M, Oliyarnyk O, Kazdová L.

PLoS One. 2015 Apr 1;10(4):e0122768. doi: 10.1371/journal.pone.0122768. eCollection 2015.

PMID:

25830228

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Targeting sphingolipid metabolism in the treatment of obesity/type 2 diabetes.

Bellini L, Campana M, Mahfouz R, Carlier A, Véret J, Magnan C, Hajduch E, Le Stunff H.

Expert Opin Ther Targets. 2015 Mar 26:1-14. [Epub ahead of print]

PMID:

25814122

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Select item 258138768.

Alpha-synuclein overexpression negatively regulates insulin receptor substrate 1 by activating mTORC1/S6K1 signaling.

Gao S, Duan C, Gao G, Wang X, Yang H.

Int J Biochem Cell Biol. 2015 Mar 23;64:25-33. doi: 10.1016/j.biocel.2015.03.006. [Epub ahead of print]

PMID:

25813876

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Select item 258098029.

Skeletal muscle ceramide species in men with abdominal obesity.

De la Maza MP, Rodriguez JM, Hirsch S, Leiva L, Barrera G, Bunout D.

J Nutr Health Aging. 2015;19(4):389-96. doi: 10.1007/s12603-014-0548-7. (Suom.  14.5. 2015)

PMID:

25809802

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Activation of sphingosine kinase 2 by endoplasmic reticulum stress ameliorates hepatic steatosis and insulin resistance in mice.

Lee SY, Hong IK, Kim BR, Shim SM, Sung Lee J, Lee HY, Choi CS, Kim BK, Park TS.

Hepatology. 2015 Mar 22. doi: 10.1002/hep.27804. [Epub ahead of print]

PMID:

25808625

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Impact of alogliptin and pioglitazone on lipid metabolism in islets of prediabetic and diabetic Zucker Diabetic Fatty rats.

Cai Y, Lydic TA, Turkette T, Reid GE, Olson LK.

Biochem Pharmacol. 2015 May 1;95(1):46-57. doi: 10.1016/j.bcp.2015.03.010. Epub 2015 Mar 20.

PMID:

25801003

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Pyruvate dehydrogenase kinase 4 (PDK4) could be involved in a regulatory role in apoptosis and a link between apoptosis and insulin resistance.

Dlamini Z, Ntlabati P, Mbita Z, Shoba-Zikhali L.

Exp Mol Pathol. 2015 Mar 18;98(3):574-584. doi: 10.1016/j.yexmp.2015.03.022. [Epub ahead of print]

PMID:

25794976

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Accumulation of ceramide in slow-twitch muscle contributes to the development of insulin resistance in the obese JCR:LA-cp rat.

Fillmore N, Keung W, Kelly SE, Proctor SD, Lopaschuk GD, Ussher JR.

Exp Physiol. 2015 Mar 19. doi: 10.1113/EP085052. [Epub ahead of print]

PMID:

25786668

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Intake of farmed Atlantic salmon fed soybean oil increases hepatic levels of arachidonic acid-derived oxylipins and ceramides in mice.

Midtbø LK, Borkowska AG, Bernhard A, Rønnevik AK, Lock EJ, Fitzgerald ML, Torstensen BE, Liaset B, Brattelid T, Pedersen TL, Newman JW, Kristiansen K, Madsen L.

J Nutr Biochem. 2015 Feb 4. pii: S0955-2863(15)00021-2. doi: 10.1016/j.jnutbio.2014.12.005. [Epub ahead of print]

PMID:

25776459

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Modulation of sphingolipid metabolism with calorie restriction enhances insulin action in skeletal muscle.

Obanda DN, Yu Y, Wang ZQ, Cefalu WT.

J Nutr Biochem. 2015 Mar 5. pii: S0955-2863(15)00040-6. doi: 10.1016/j.jnutbio.2015.01.007. [Epub ahead of print]

PMID:

25771159

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Glucose Induces Sensitivity to Oxygen Deprivation and Modulates Insulin/IGF-1 Signaling and Lipid Biosynthesis in Caenorhabditis elegans.

Garcia AM, Ladage ML, Dumesnil DR, Zaman K, Shulaev V, Azad RK, Padilla PA.

Genetics. 2015 May;200(1):167-84. doi: 10.1534/genetics.115.174631. Epub 2015 Mar 10.

PMID:

25762526

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Effects of inhibitors of key enzymes of sphingolipid metabolism on insulin-induced glucose uptake and glycogen synthesis in liver cells of old rats.

Babenko NA, Kharchenko VS.

Biochemistry (Mosc). 2015 Jan;80(1):104-12. doi: 10.1134/S0006297915010125.

PMID:

25754045

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Select item 2566540618.

[Sphingolipids in skeletal muscles of C57B1/6 mice after short-term simulated microgravity].

Bryndina IG, Shalagina MN, Ovechkin SV, Ovchinina NG.

Ross Fiziol Zh Im I M Sechenova. 2014 Nov;100(11):1280-6. Russian.

PMID:

25665406

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New evidence for the role of ceramide in the development of hepatic insulin resistance.

Konstantynowicz-Nowicka K, Harasim E, Baranowski M, Chabowski A.

PLoS One. 2015 Jan 30;10(1):e0116858. doi: 10.1371/journal.pone.0116858. eCollection 2015.

PMID:

25635851

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Select item 2561705120.

Involvement of the insulin-like growth factor binding proteins in the cancer cell response to DNA damage.

Chua MW, Lin MZ, Martin JL, Baxter RC.

J Cell Commun Signal. 2015 Jan 25. [Epub ahead of print]

PMID:

25617051

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