https://www.crsociety.org/topic/11488-cold-exposure-other-mild-stressors-for-increased-health-longevity/page-18
Here is a schematic diagram based on insight gathered from [1] depicting the feedback loops between WAT, BAT and Beige Fat triggered as a result of cold exposure:

As you can see, cold exposure induces BAT activity, which not only generates heat by burning glucose and fats via UCP1 but also releases FGF21. The FGF21 causes WAT to synthesize health-promoting adiponectin, as well as undergo "browning" to become beige fat by synthesizing more mitochondria and UCP1, which in turn generates more heat, and more FGF21 in a positive feedback loop.
Inga kommentarer:
Skicka en kommentar